Day 1

Thursday, May 14

08:00–19:00 · 5 sessions · 3 symposia

09:15–09:25

COMy 2026 kick-off: Welcome by the Congress Chairs

09:25–10:40

Session 1

Moderators: Hervé Avet-Loiseau, France; Rafael Fonseca, USA

Time Topic Speaker
09:25–09:40 Genomics Francesco Maura, USA
09:40–09:55 Microenvironment Madhav Dhodapkar, USA
09:55–10:10 Role of immune microenvironment in myeloma Paola Neri, Canada
10:10–10:25 Liquid biopsies Joaquín Martínez López, Spain
10:25–10:40 Discussion All session faculty and Gareth Morgan, USA + Mehmet Samur, USA

10:40–11:00

Coffee Break

11:00–12:15

Session 2

Moderators: Rafat Abonour, USA; Heinz Ludwig, Austria

Time Topic Speaker
11:00–11:15 Historical perspective Joan Bladé, Spain
11:15–11:30 Summary of new response criteria Shaji Kumar, USA
11:30–11:45 Role of MRD Susan Bal, USA
11:45–12:00 Role of SFL chains and role of urine Kwee Yong, UK
12:00–12:15 Mass spectrometry Noemi Puig, Spain

13:30–14:00

Lunch Break

14:00–15:15

Industry-supported Symposium

by J&J

Weaving evidence into practice: expert perspectives on treating NDMM in 2026

15:15–16:30

Session 3

Moderators: Faith Davies, USA; Marc Raab, Germany

Time Topic Speaker
15:15–15:30 Resistance to CAR T Carlos Fernández de Larrea, Spain
15:30–15:45 Resistance to bispecifics Hermann Einsele, Germany
15:45–16:00 Resistance to ImiDs Keith Stewart, Canada
16:00–16:15 Overcoming resistance Nizar Bahlis, Canada
16:15–16:30 Discussion All session faculty and Malin Hultcrantz, USA + Michael O’Dwyer, Ireland

16:30–16:50

Coffee Break

16:50–17:50

Session 4

Moderators: Wee Joo Chng, Singapore; Noopur Raje, USA

Time Topic Speaker
16:50–17:05 Smoldering multiple myeloma María-Victoria Mateos, Spain
17:05–17:20 Waldenstrom Disease Steven Treon, USA
17:20–17:35 Amyloidosis Suzanne Lentzsch, USA
17:35–17:50 Discussion All session faculty and Rahul Banerjee, USA

17:50–19:00

Session 5

Moderators: Meral Beksaç, Turkey; Vania Hungria, Brazil

Time Topic Speaker
17:50–18:05 New classification Jill Corre, France
18:05–18:20 Extra-medullary disease Saad Usmani, USA
18:20–18:35 Plasma cell leukemia Cyrille Touzeau, France
18:35–18:50 Functional high-risk Martin Kaiser, UK
18:50–19:00 Discussion All session faculty and Luciano Costa, USA + Rakesh Popat, UK

Day 2

Friday, May 15

07:00– · 7 sessions · 5 symposia

07:00–08:00

Session 6

Webinar showcase from IACH I: Educating Patients for Better Outcomes
Time Topic Speaker
Video Session

08:00–09:15

Industry-supported Symposium

by Adaptive

09:15–10:30

CME Symposium

by MJH Life Sciences

Medical Crossfire: Turning Therapeutic Innovation Into Practice-Personalizing Care in Multiple Myeloma

10:30–11:00

Coffee Break

11:00–12:00

Session 7

Moderators: Mohamad Mohty, France; Jean-Luc Harousseau, France

Time Topic Speaker
Discussion: How to translate the new CURE definition into real-world clinical practice
Panelists:
Gösta Gahrton, Sweden
Catarina Geraldes, Portugal
Irene Ghobrial, USA
Sagar Lonial, USA
Vincent Rajkumar, USA
Jesús San Miguel, Spain

13:20–13:50

Lunch Break

Time Topic Speaker
Video Session during the Lunch Break

13:50–14:25

Session 9

Chairs: Mohamad Mohty, France; María-Victoria Mateos, Spain; Arnon Nagler, Israel

Time Topic Speaker
Awards Presentations
Jean-Luc Harousseau Award
Multiple Myeloma Pioneers Award
Women in Multiple Myeloma Achievement Award

14:25–15:40

Industry-supported Symposium

by Gilead and Kite

15:40–16:40

Session 10

Chairs: Philippe Moreau, France; Nikhil Munshi, USA

16:40–17:55

Industry-supported Symposium

by Pfizer

Unmet Needs in RRMM: Evolving BsAb Therapy From Inpatient to Outpatient Settings

17:55–18:15

Coffee Break

18:15–19:45

Session 11

Moderators: Thierry Facon, France; Francesca Gay, Italy

Time Topic Speaker
18:15–18:35 Elderly patients Salomon Manier, France
18:35–18:55 TE patients Aurore Perrot, FranceSupported by an unrestricted educational grant from Amgen
18:55–19:15 Bone disease Evangelos Terpos, Greece
19:15–19:30 Thrombosis in myeloma Uriel Suárez, Spain
19:30–19:45 Discussion All session faculty and Faisal Basheer, UK + Holly Lee, Canada
Time Topic Speaker
Video Session

Day 3

Saturday, May 16

07:00–20:00 · 6 sessions · 5 symposia

07:00–08:00

Session 13

Chairs: Claudio Cerchione, Italy; Nour Moukalled, Lebanon

Time Topic Speaker
07:00–07:20 Case discussion 1 Arthur Bobin, France
07:20–07:40 Case discussion 2: thrombosis in myeloma Emilie Chalayer, France
07:40–08:00 Discussion All session faculty and Jean Marc Schiano De Colella, France + Uriel Suárez, Spain

08:00–09:15

Industry-supported Symposium

by Sebia

09:15–10:30

CME Symposium

by Decera Clinical Education

Redefining Myeloma Care: An Expert Roundtable on the Potential of Novel Strategies Across the Disease Spectrum

10:30–10:50

Coffee Break

10:50–12:00

Session 14

Moderators: Chandramouli Nagarajan, Singapore; Joshua Richter, USA

Time Topic Speaker
10:50–11:10 The case for peptide conjugates Elena Zamagni, ItalySupported by an unrestricted educational grant from Oncopeptides
11:10–11:30 NDMM under dialysis Florent Malard, France
11:30–12:00 Discussion All session faculty and Doris Hansen, USA + Xavier Leleu, France + Hira Mian, Canada

12:00–13:15

Industry-supported Symposium

by GSK

The Evolving Role of ADC-Based BCMA Targeting in RRMM: Evidence-Led Practicalities of Early Intervention

13:15–13:45

Lunch Break

13:25–13:40

Session 15

Webinar showcase from IACH III: Bispecific Antibodies in Multiple Myeloma: Practical Strategies for Safe and Effective Delivery
Time Topic Speaker
Video Session

13:45–14:50

Session 16

Moderators: Michel Delforge, Belgium; Thomas Martin, USA

Time Topic Speaker
13:45–13:55 1st relapse, the case for CAR T cells Luciano Costa, USA
13:55–14:05 1st relapse, the case for Ab drug conjugates Meletios (Thanos) Dimopoulos, Greece
14:05–14:15 Discussion Debate faculty and Roman Hajek, Czech Republic + Andrzej Jakubowiak, USA
14:15–14:25 Doublet maintenance Paul Richardson, USA
14:25–14:35 Single agent maintenance Pieter Sonneveld, Netherlands
14:35–14:50 Discussion Debate faculty and Hartmut Goldschmidt, Germany + Andrew Spencer, Australia

16:05–17:20

Industry-supported Symposium

by Regeneron

Beyond Head-to-Head Trials: Answering Real Myeloma Questions – What Matching-Adjusted Indirect Comparisons (MAICs) Show and What They Don’t

17:20–17:30

Coffee Break

17:30–19:30

Session 17

Moderators: Jesús Berdeja, USA; Joy Ho, Australia

Time Topic Speaker
17:30–18:00 35 years of myeloma trials Philippe Moreau, France
18:00–18:30 Genomics guiding therapy Nikhil Munshi, USA
18:30–19:00 The future of multiple myeloma therapy Kenneth Anderson, USA
19:00–19:30 Discussion All session faculty and Mohamad Mohty, France + Arnon Nagler, Israel

19:30–20:00

Session 18

COMy in-person conclusions

Day 4

Sunday, May 17 Online only

10:00–12:30 · 2 sessions

10:00–11:05

Session

Moderators: Mohamad Mohty, France; María-Victoria Mateos, Spain; Arnon Nagler, Israel

Time Topic Speaker
10:00–10:10 Daratumumab (Dara) Monotherapy vs. Active Monitoring (ActMon) in Patients with High-Risk Smoldering Myeloma (SMM): AQUILA Outcomes based on Mayo 2018/IMWG 2020 Risk Stratification, IMWG 2020 plus Cytogenetic Criteria, and Age Philippe Moreau, France
10:10–10:20 ARLOCABTAGENE AUTOLEUCEL (ARLO-CEL) IN PATIENTS WITH HEAVILY PRETREATED RELAPSED/REFRACTORY MULTIPLE MYELOMA (RRMM): FINAL ANALYSIS FROM THE PHASE 1 STUDY Susan Bal, USA
10:20–10:30 Effectiveness of bridging therapy corresponds to improved outcomes after ciltacabtagene autoleucel (cilta-cel): phase 3 CARTITUDE-4 study of patients with relapsed, lenalidomide-refractory multiple myeloma Xavier Leleu, France
10:30–10:40 BELANTAMAB MAFODOTIN, BORTEZOMIB, AND DEXAMETHASONE (BVd) VS DARATUMUMAB, BORTEZOMIB, AND DEXAMETHASOME (DVd) IN RELAPSED/REFRACTORY MULTIPLE MYELOMA (RRMM): LONG-TERM RESPONDER ANALYSIS OF THE PHASE 3 DREAMM-7 TRIAL Presented by Vania Hungria, Brazil joined by María-Victoria Mateos, Spain for the discussion
10:40–10:50 SUBGROUP ANALYSIS OF DREAMM-7 AND DREAMM-8: OUTCOMES WITH BELANTAMAB MAFODOTIN (BELAMAF) IN PATIENTS WITH FUNCTIONAL HIGH-RISK (FHR) RELAPSED/REFRACTORY MULTIPLE MYELOMA (RRMM) María-Victoria Mateos, Spain
10:50–11:05 Discussion

11:05–11:15

Break

11:15–12:20

Session

Moderators: Mohamad Mohty, France; María-Victoria Mateos, Spain; Arnon Nagler, Israel

Time Topic Speaker
11:15–11:25 Isatuximab in Combination with Lenalidomide and Dexamethasome (Isa-Rd) in Patients with High-Risk Smoldering Multiple Myeloma (HR-SMM): Phase 3 ITHACA Study Final Safety Run-in (SRI) Results María-Victoria Mateos, Spain
11:25–11:35 Safety Results from REALiTEC Cohort 2: A Multi-Country Observational Study of Teclistamab in Relapsed/Refractory Multiple Myeloma in Real World Rakesh Popat, UK
11:35–11:45 BELANTAMAB MAFODOTIN (BELMAF) IN COMBINATION WITH BORTEZOMIB, LENALIDOMIDE, AND DEXAMETHASONE (VRD) FOR PATIENTS (PTS) WITH TRANSPLANT-INELIGIBLE (TI) NEWLY DIAGNOSED MULTIPLE MYELOMA (NDMM): A FOCUS ON TREATMENT EFFICACY AND MANAGEMENT/RESOLUTION OF OCULAR EVENTS IN THE PHASE 1 DREAMM-9 STUDY Saad Usmani, USA
11:45–11:55 COMPARATIVE EFFICACY OF LINVOSELTAMAB VERSUS IDECABTAGENE VICLEUCEL (IDE-CEL) AND CILTACABTAGENE AUTOLEUCEL (CILTA-CEL) IN TRIPLE-CLASS EXPOSED (TCE) RELAPSED/REFRACTORY MULTIPLE MYELOMA (RRMM): A MATCHING-ADJUSTED INDIRECT COMPARISON (MAIC) Joshua Richter, USA
11:55–12:05 PATIENTS WITH RELAPSED/REFRACTORY MULTIPLE MYELOMA (RRMM) WHO ACHIEVED SUSTAINED MINIMAL RESIDUAL DISEASE-NEGATIVITY WITH BELANTAMAB MAFODOTIN (BELAMAF) TREATMENT IN DREAMM-7 María-Victoria Mateos, Spain
12:05–12:20 Discussion

12:20–12:30

Conclusion and see you next year!